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The present research work investigates the potential of combining Lean Production and Industry 4.0 explicitly by IoT solutions as well as digital twins at manufacturing companies in Germany, Austria and Switzerland. First, elementary concepts of lean management and Industry 4.0 are discussed. The paper then focuses on the content of IoT solutions and digital twins. For this purpose, five small and medium-sized manufacturing companies are used, which are examined by means of qualitative, semi-structured guideline interviews, in order to provide valuable results regarding the current state, effects, potentials as well as challenges of both technologies. The results show that IoT solutions and digital twins are already partly under establishment and further development. The consequences are numerous advantages, which enable a more efficient way of working. However, due to a lack of regulations and limited financial resources, small and medium-sized enterprises tend to be hesitant regarding the implementation of new technologies. This work provides valuable insights into the day-to-day work of manufacturing companies in the DACH region, which are currently facing the challenges, seeking the potential and seeing initial successes with the help of IoT and digital twin.