Open Access

Lars Hoitink, Carmen Castillo, Joan Quetglas, I-Chen Chung, Nina Deutsch

• The longevity industry has been expanding for several years now, with the goal to prolong not only the lifespan of people but also their healthspan. One of the most remarkable techniques in the field is the CRISPR Cas-9 gene-editing tool, which owing to its flexibility and efficiency, allows humans to develop new treatments to prevent or cure a great variety of diseases. This paper aims to forecast the future state of the CRISPR Cas-9 technology in Germany in 2035 by using the INKA 4 scenario manager software. A total of five areas of influence –– i.e. scientific, economic, demographic, ethical, and legal –– were identified. From those, 11 descriptors were created based on relevant scientific literature and were introduced in the INKA software to develop the scenarios. This process resulted in three clearly differentiated scenarios that exhibit high probabilities of a positive outlook for the CRISPR-Cas9 technology in Germany by 2035.