Open Access

Subject of the thesis at hand is the analysis of symmetric block ciphers with a block length of 32 bit. It is meant to give a comprising overview over the topic of 32 bit block ciphers. The topic is divided in the examination of three questions. It contains a list of state of the art block ciphers with a block length of 32 bit. The block ciphers are being described, focussing on the encryption function. An SPN-based cipher with 32 bit block length is being proposed by rescaling the AES cipher. The 32 bit block length results in certain security issues. These so called risk factors are analysed and mitigating measures are proposed. The result of the thesis is, that 32 bit block ciphers can be implemented in a secure manner. The use of 32 bit ciphers should be limited to specific use-cases and with a profound risk analysis, to determine the protection class of the data to be encrypted.

This thesis investigates the effect choice options in e-commerce applications have on consumers’ decision making. Previous research showed that a large number of options can affect consumers negatively. However, the conditions for such choice overload are unclear. After reviewing the existing research, the amount of information (entropy) contained in a choice set and individual differences were determined as possible influencing factors in an online environment. In a choice experiment, choice sets with varying information loads and an assessment of the Big Five personality traits were used to test the impact of the two identified factors on choice avoidance behavior. Results from chi-square-tests and a logistic regression model suggest choice overload but without entropy having an effect. A logistic regression model revealed that extraverted consumers are easier overloaded. A low Neuroticism score was found to be related to less occurrence of a too-much-choice-effect. Consumers with a high Openness score on the other hand choose one of the presented options more often and were therefore less often overwhelmed by the assortment. An interaction effect between personality and the amount of entropy was not found. These findings extend the research on choice overload and offer valuable input for marketers targeting consumers online.

Mobile diagnostics – or mobile health in general – is highly appealing, not only for clinicians, but also for patients. It implies empowerment, in particular of those who are really in need, such as inhabitants of less developed regions within the world who have limited access to healthcare. It also implies simplification: Easy data management – a continuous flow of information. Therefore, development of miniaturized and highly integrated diagnostic systems allowing near patient “instant” diagnostics gain a lot of momentum since more than a decade. However, system integration requires time and a significant amount of investment. In addition, there is strong competition on resources from other emergent technologies, such as next generation sequencing which made the collection of e.g. human genome data less expensive and much faster. A more severe challenge is that mobile diagnostics require a change in healthcare management, e.g. towards integrated practice units. This, in turn, requires implementation of adequate reimbursement, standards of interoperability, training of staff, quality control. In 2010, Germany’s Federal Ministry of Education and Research (BMBF) launched the grant initiative Mobile Diagnostic Systems (MD, 2011─2015) as part of its high-tech strategy. MD aimed at generating knowledge on how microsystem technologies fit into German healthcare environments. On the basis of interviews with multidisciplinary MD actors, this thesis evaluated retrospectively how the publicly funded innovation network managed to overcome pre-defined external barriers of diffusion, including technology, regulatory affairs and market access. Retrospectives reveal internal barriers involving knowledge and technology transfer, negatively influencing generation of innovation. In particular, financing still represents a high hurdle for biotech innovators in Germany: Larger firms look predominately for market-ready or in-market technologies rather than prototypes and venture capitalists are rare or extremely risk-averse. Another important finding was, that actors involved were highly focused on individual work packages. This risks of not seeing the whole environment embedding MD. Consequently, potential opportunities may be missed, e.g. synergies with relatively close (DIALOC) or more distant initiatives (Global Health Delivery Project-based discussion rounds). This could be partly due to the fact that publicly funded networking activities provide less freedom-to-operate because of pre-defined milestones. In addition, further development of actors with respect to role playing (e.g. boundary spanning or innovation selling) is often not included in such “innovation packages”, but can help to maneuver change. Internal barriers need to be addressed first before targeting the major remaining external hurdle: Reimbursement. Although the latter was covered within MD, standardization of technology evaluation is still an unmet need which strongly influences the willingness-to-implement novel mobile diagnostics. Thus, the value added is to be demonstrated to justify adequate reimbursement. Achieving this goal can be successful, when innovation networking finds its path towards a common vision, e.g. towards value-based integrated healthcare. Pathfinding and visioning can be facilitated by process promoter with excellent network management capabilities. In addition, such a promoter could help to further develop engagement, openness and commitment of collaborators. Therefore, transfer of MD activities to established “top” networks or clusters is recommended for securing valuable knowledge generated. In this environment, an important next step – globalization of MD for ensuring future return on investment – could be triggered as well. Since MD innovation was found to involve both product and service innovation, maneuvering change is particularly challenging for small and medium sized enterprises. These could benefit from engagement in innovation networking. Findings of this case study can help all direct and indirect actors in the field of MD innovation or in other high complex environments to reconsider pathfinding as well as role playing in networking.