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Clinical Research is expanding into an international and more regulated environment, specifically its quality management. Pharmaceuticals and Research Organizations are investing significant amounts of money as well as the regulatory agencies. The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) are improving and developing regulations and meetings to standardize globally these practices. Therefore this Thesis integrates and extends the FDA and EMA recommendation of implementing “Risk based quality management” in Clinical Research protocol execution with a multisource point of view and the proposal of adding a Risk Management Report as an output, which will work also as an input for future protocols implementation. Diverse articles and regulations related with Quality Management and Clinical Research Processes were reviewed to work as a base for the analysis of this thesis. Risk Based Quality Management is the actual trend and newly implemented process to improve quality in clinical research. The goal of this Thesis is to combine the different actual factors, methods and regulations in order to expand Risk Based Quality Management and reach a better degree in quality and standardization. The question therefore is whether this redesigned Risk Based Quality Management process can really be incorporated with the actual practices, and if it is possible to adopt it in Clinical Research.
Globally operating stamping and hybrid parts manufacturer KRAMSKI and the FRANUHOFER IPA have developed a new prosthetic foot designed for developing countries. Although low-cost solutions in developing countries exist, these significantly lack functionality. The new prosthetic foot will be more expensive than most low-cost alternatives, which start from $ 5.00 for a simple SACH foot, but can be sold for a much lower price than most high-tech prosthetics imported from industrialized nations, which can cost more than $5,000. The purpose of the paper was to determine the market potential for the prosthetic foot, to monitor the competition and to create an overall marketing concept for distributing and promoting the product. Therefore market and competitor analyses were conducted. On base of the market and competitor research, strategies were formulated. As a last step, the marketing mix with its four elements was regarded and different distribution and promotional tools have been reviewed to propose marketing activities that could be undertaken by KRAMSKI. Since six different target countries in Asia and Latin America (India, Sri Lanka, Cambodia, El Salvador, Guatemala, and Honduras) were chosen in agreement with KRAMSKI, the market potential for each of these countries was estimated. Two different approaches were used to estimate the market potential of each country. Following the first approach, the total market demand of all six countries added up to more than 5.6 million potential. The second approach added up to a total of 6.7 million potential customers for the target regions. The numbers revealed that 95 % of all lower limb amputees lived in India. Therefore India has been chosen as the target country for all further research in the paper. The monitoring of the market change revealed that prosthetic foot demand was going to increase over the next decades due to lost limbs through road traffic incidents and diabetes. Besides, by the year 2030 most of the world’s middle class (80 %) will be living in developing countries As a consequence, more people will be able to afford health care products such as prosthetic feet. It has been found out that customers in developing countries lay emphasis on either low cost or quality. As a second step, the competitive environment within the prosthetic foot sector in India has been analyzed. Although the Indian healthcare system is still underdeveloped, the sector offers future opportunities for the private sector. The biggest commercial manufacturers of prosthetic feet in India are Otto Bock, Endolite and Streifeneder-Collegepark. But also international and local NGOs, such as BMVSS (Bhagwan Mahaveer Viklang Sahayata Samiti) with the Jaipur Foot, distribute prosthetic feet. Most of the commercial products are significantly more expensive than the products distributed by NGOs. Most NGOs manufacture prosthesis by themselves in order to save costs and create jobs. Many amputees can receive the prostheses and service for free due to donations which finance the NGOs. The competitive suppliers either own fitting centers or distribute their products through local wholesalers. On base of the market, consumer segmentation has been conducted. The Indian population has been divided into different income levels. Rural aspirers and urban seekers could be seen as the most profitable target segments, but urban customers might be easiest to reach due to location. In a last step, the marketing mix for the prosthetic foot has been analyzed. The prosthetic foot should offer specific features to align with developing countries. The product needs to be priced according to company objectives, demand, cost and competition. Since KRAMSKI does not yet have the capabilities and resources to fit prosthetic feet, the company needs to distribute to the end-user through indirect distribution channels such as wholesalers, clinics and NGOs. Therefore an important activity for KRAMSKI is the acquisition of distribution channels. This can be approached through promotional tools such as personal selling, direct marketing, online marketing or the participation on trade fairs and exhibitions.
The purpose of this thesis is to investigate the fairly recent Basel III regulations, and to find out if they have impacts on the financing of small and medium-sized enterprises. Therefore, the theoretical impacts on financial institutions and on small and medium-sized enterprises would be analysed and compared to the real development. Basel III is an advancement to Basel I and II and contains stricter capital and liquidity requirement regulations for financial institutions, as well as a leverage ratio. The purpose is to create a financial sector, which would be more resistant against crises. Because the liquidity requirements and the leverage ratio are not, or only partly introduced yet, the thesis focuses more on the capital requirements. These requirements, demand banks to deposit a higher percentage of equity for each credit operation, depending on the risk. It is expected that financial institutions will face an excess need of capital to fulfil the requirements. On the one hand, banks could increase their equity, which hypothetically could lead to higher capital costs as well as an increase of credit costs. That would in turn result in worse credit terms for SMEs. On the other hand, banks could reduce their risk-weighted assets to lower the need for new capital. That could minimize the capacity of the credit business and lead to difficulties for SMEs in obtaining a loan. An empirical study, based on a theoretical simulation, came to the result that there will be a slight worsening of the credit terms and the credit supply for SMEs. Regarding to the question “if the new capital requirements are appropriate for SME-loans”, it shows that there is no increase of risk in that segment. Therefore, the capital requirements should be adjusted for these kind of loans. The theoretical impacts of the liquidity requirements and the leverage ratio are also expected to affect the loans for SMEs, which are the second important financing instrument. To compare and analyse the theoretical impacts to the real development, latest empirical studies were used to get a picture of the current situation. It shows that the group of financial institutions that are relevant for SME-loans have a moderate increase in their equity basis and almost no decrease of their risk-weighted assets. Theoretically, that should lead to worse credit terms and no change in the credit supply. While analysing the realised external funds made in recent years, it is affirmed that there is no decline in the credit supply. Regarding the increased capital basis, there is no worsening in the credit terms perceived in the reality. The favourable key interest rate could be the reason for that, because it compensates the increased capital cost. Hence, Basel III does not represents a threat to the mid-sized sector in average. However, it can be stated that, the smaller the enterprises are, the more difficult it is to get a loan and the worse the conditions are.
Diese Arbeit behandelt die Thematik der Kundenzufriedenheit, welche in Forschung und Praxis auf Grund ihres hohen Einflusses auf den Unternehmenserfolg nach wie vor an Bedeutung gewinnt. Anhand des Beispiels der SCOPE Messestrategie GmbH, Veranstalter der HORIZON Messe für Studium und Abiturientenausbildung, wird die
Vorgehensweise bei der Durchführung einer Kundenzufriedenheitsanalyse im Messewesen dargelegt. Die Ergebnisse dieser Analyse zeigen, welchen Dienstleistungseigenschaften einer Bildungsmesse besondere Bedeutung beizumessen ist und wie man auf Basis dieser Erkenntnisse eine Steigerung der Ausstellerzufriedenheit bewirken kann.
Background
The recent worldwide financial crisis that occurred in last quarters of 2007 up until mid 2009 was accompanied by the massive failure of many financial institutions and liquidity providers. Investment banks and other institutionalized financial investors were unsuccessful in producing any real returns for their clients. This drastic fail in all the other traditional investments led to the questioning of how well the hedge fund industry performed in this light based on their promise as absolute return producers regardless of the market environment. This paper seeks to analyse the performance of the Long/Short Equity Strategy in particular relative to the performance of the overall market.
Methods
Thorough examination and validation of numerous empirical studies which have already been carried out on the subject matter are brought to light through the analysis of available historical data of the returns posted by these funds during the crisis using generally accepted statistical funds’ assessment tools giving an adequate angel to the performance of Long-Short Equity hedge Funds especially at the heart of the financial crisis in the last quarters of 2007 to mid 2009.
Results
Equity Long/Short Hedge funds as every other strategy in they industry succeeded in 2008 in outperforming other traditional investment vehicles and the broad stock an bond markets although the failed in to produce the absolute returns promised to their investments. In 2009 they posted similar results to that of S&P 500 index with subsequent declines in 2010 and 2011 thus failing to period their returns where highly correlated with that of the overall market coined with negative skewness and high kutorsis.
Conclusion
Even though hedge funds succeeded in outperforming the market in the heart of the crisis, they failed to provides their investors with absolute returns and also the benefits which the provide in terms of diversification to reduce the exposure of their funds to market risk was limiting. The very high fees paid to them by investors was not justified by their performance.
Optimizing the grinding process through reduction of the loading of grinding tool by infiltration
(2015)
Vollautomatisiert umformen
(2015)
Global Sourcing - ,,von der Theorie in die Praxis'' - Analyse alternativer Beschaffungsmärkte
(2015)
Steigender Wettbewerbsdruck im Zuge der Globalisierung zwingt Unternehmen dazu, sich noch stärker von der Konkurrenz abzuheben. Wesentlicher Erfolgsfaktor ist neben dem Absatz innovativer Produkte auch zunehmend die Beschaffung der erforderlichen Komponenten zur Herstellung dieser Produkte. In diesem Zusammenhang hat sich in den letzten Jahren der Begriff Global Sourcing in der Beschaffungsabteilung von Unternehmen etabliert. Dabei geht es um die Ausweitung der Beschaffungsaktivitäten auf weltweite Anbietermärkte. Andere Länder können durch unterschiedliche Bedingungen bestimmte Produkte zu besseren Konditionen anbieten als der Heimatmarkt. Um von diesen Vorteilen profitieren zu können muss überprüft werden, ob Alternativen auf internationalen Märkten bestehen und ob diese nachhaltig genutzt werden können. Der Inhalt der vorliegenden Bachelor-Thesis stellt die Analyse internationaler Beschaffungsmärkte dar. Das Unternehmen ARBURG GmbH + Co KG hat diese Potenziale erkannt und ist bestrebt, diese weiter voranzutreiben. Das Ergebnis dieser Arbeit liefert neue Erkenntnisse bezüglich internationaler Lieferantensuche, - bewertung und -auswahl. Dabei wurde überprüft, ob für bestimmte Produktgruppen alternative Lieferanten identifiziert werden können, die ihre Produkte zu besseren Konditionen als bisherige Lieferanten anbieten. Die Ergebnisse wurden als erfolgsversprechend eingestuft, lassen Schlüsse für weitere Beschaffungsaktivitäten zu und können in eine ganzheitliche Strategieableitung des Unternehmens integriert werden. Ausgewählte Methoden und Konzepte wurden dabei angewendet, um eine nachvollziehbare und zukünftig anwendbare Vorgehensweise zu etablieren.
This paper analyzes the importance of recommender systems for B2C e-Commerce businesses, using extensive literature review as well as a consumer survey. Readers will gain a basic understanding on how the technology behind the recommendation works, how competitiveness in e-Commerce can be defined and what the consumer perspective on recommender systems is. The paper will ultimately provide valuable insights into how recommender systems can create a major competitive advantage for online retailers and why an online-shop without a recommender engine will struggle to stay or become competitive.
Content of this bachelor thesis is to portray the status quo in Germany´s discussion about its welcoming culture and its lack of qualified workers. Government actions as well as efforts from companies are shown in this paper. Two surveys were conducted about the welcoming culture in Germany and German companies. The first survey was asking companies about their need of qualified workers as well as an already might existing welcoming culture. The second survey was sent to qualified immigrants who came through projects to Germany, to find out how they perceived the efforts for a welcoming culture in Germany. The results of the whole research are summed up in the last part of the thesis with a critical eflection. The surveys were conducted with the support of Synergie Personal GmbH Deutschland, as well as with the help of the companies that participated in the projects of the Fachkräfteallianz Gewinnerregion.
Commissioning rules for optimal velocity controller damping of servo axes using elimination methods
(2015)
In cooperation with the Customer Relationship Management and Communication department at Volkswagen AG the thesis “The future of Service Marketing in the automotive industry” was written. The sales part of After Sales is relatively small compared to the total turnover, but it is the biggest part of benefits of a car manufacturer. This is just one reason why After Sales has such a big relevance in the automotive industry. This thesis defines After Sales and Service Marketing, gives reasons for the importance of After Sales and details how to attract the right customer groups in the context of After Sales. Additionally, it is discussed how customer needs are best addressed and fulfilled, and what kind of new Service Marketing tools could help Volkswagen to exploit the full market potential of its after sales division. The data on which this paper is based was drawn from various company-internal and external sources. The most important company-external data sources were articles about the after sales practices of other car manufacturers and companies of completely different industries. With regards to internal sources, this paper is based on internal best practices and data collected in an expert workshop regarding the internal visions that are shaping the future of Service Marketing. The given data was qualitatively analysed and resulted in a collection of potential Service Marketing tools for the international Brand Volkswagen Cars markets. The most important findings are new digital communication tools, new customer relationship tools and point of sales tools.
In the last 30 years academics were exploring the field of ethical consumption and identified an attitude - behavior gap in the decision making process. Since then diverse studies have been implemented to understand ethical consumers' attitudes, motives and behavior. Parallel to the academic research being developed, there had been an increasing interest from the consumer side in behaving and consuming more ethically. Particularly, consumers have inclined their ethical purchases towards fair trade products. The present exploratory research implemented a quantitative metaphoric method called Zaltman Elicitation Metaphoric Technique (ZMET) to further contribute in the literature of ethical and fair trade consumption. The ZMET in-depth interviews were carried out with 10 German fair trade food consumers during the months of February and March in 2015. The results revealed a connection between participants' feelings, emotions, personal values and fair trade food consumption; likewise the research identified an association of fair trade to sustainability.
The aim of this Bachelor Thesis is to analyze the child safety lock offered by Samsung, which is one of the latest inventions on the market for Smartphones. It will be discussed if its abilities are a solution for ethical problems, which come along with Mobile Marketing on children. Furthermore it will be identified if the child safety lock, as a product, keeps the promises Samsung made to the consumers. Smartphones are gaining greater importance in today’s society and are not only used by adults, but by a great amount of children. A smartphone gives kids the possibility to enter the internet without barriers. They have access to all the offered websites and programs the internet contains, which opens up a lot of dangers. Marketing on children is getting more intensive, because children play a more important role in the buying decisions of their families than they did in the past. There are plenty of studies where children´s perception of advertisement was analyzed. A relationship between their perception of advertisement and the development of their cognitive thinking was detected. The more distinctive the cognitive thinking is, the better is their perception of advertisement.
Advertisement and other marketing methods can influence and manipulate children, without them realizing it. Due to that there a discussions on ethical level about the fairness of confronting children with contents they can´t understand because of their stage of development. Notably mobile marketing describes a lot of dangers for children owing to its availability on a Smartphone 24/7.
The two most important laws regarding media protection for children is the “Jugendschutzgesetz” (JuSchG), which is administrated by the German government and the “Jugendmedienschutz-Staatsvertrag”, which is in hands of the 16 federal states in Germany. The opinion of experts in the field of media education, as well as the opinion of parents and teachers about the mentioned topics is essential to bring different stakeholders into the account. This paper contains several empirical research methods which discuss these opinions. Key words: Marketing and Ethics, Smartphones, Marketing aimed on children, Mobile Marketing, Media Protection for children
The purpose of this study is to research the impact of enterprise social software on performance management in order to explain the statement of this thesis: performance management can benefit from social software. The thesis first defines the emergent collaborative performance management and enterprise social software systems against the background of the need for ‘modernized’ Human Resource systems. Then, interviews were conducted in order to determine the critical success factors of implementing enterprise social software into business systems and processes. Finally, the derived critical success factors are discussed and compared to different assumptions that are made in literature about the impact of enterprise social software on performance management.
It was concluded that performance management can benefit from enterprise social software, but under specific conditions such as rules and policies. Organizations that embrace new technologies and use enterprise social software in compliance with their objectives, strategies and policies can enjoy increased productivity and a collaborative business culture with highly engaged employees.
The topic of change management gained significant importance within recent years. Through the internationalization of markets, became relevant to consider factors such as intercultural management and communication. Often managers are not able to control and coordinate these projects in an adequate manner.
One of the main reasons is the c different mindsets, expectations, ideas and working styles. During the planning and execution of change projects there is much focus on the strategy and the lead project teams. Nevertheless, employ because the foreign workforce as a whole consists of many different people from various
countries and cultures. Ensuring that a change can successfully be applied at all locations is a major task and failing in managing those varieties can lead to failure of the entire change. The regional management is often faced with inadequate decisions or poor communication by the headquarters. Additionally, even more than normal mid able to work with decisions they do not understand or support required to follow instructions from the other side of the world requires various skills. The purpose of this research is to identify the requirements of good communication a
management in regional offices in this context and to analyze how a well defined scope of responsibilities can lead an international change project to success.
The German-French personnel consultancy Rheinbrücke Consulting intended to gain a deeper knowledge of the German market for personnel consulting. Due to the lack
of comprehensive literature, expert interviews were conducted in the framework of this thesis in order to analyse the structure of the German market for personnel consulting how it is changing and to derive consequences for the positioning of Rheinbrücke Consulting today and in the future. The result is that the German market for personnel consulting is opaque and that a lot of companies from sole entrepreneurs to personnel consulting concerns supply a lot of services that vary considerably in their quality. Potential clients prefer to employ recommended personnel consultancies that are specialised and supply performance-based billing. They aim for long term business partnerships with personnel consultancies wherefore the author recommends to Rheinbrücke Consulting to follow up in their strategy work with the key subjects networking, relationship between customer and personnel consultancy, specialisation and remuneration.