Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction
Author: | Roman C. Hillig, Brice Sautier, Jens Schroeder, Dieter Moosmayer, Andre Hilpmann, Christian M. Stegmann, Nicolas D. WerbeckGND, Hans Briem, Ulf Boemer, Joerg Weiske, Volker Badock, Julia Mastouri, Kirstin Petersen, Gerhard Siemeister, Jan D. Kahmann, Dennis Wegener, Niels Böhnke, Knut Eis, Keith Graham, Lars Wortmann, Franz von Nussbaum, Benjamin Bader |
---|---|
URN: | https://urn:nbn:de:bsz:fn1-opus4-71469 |
DOI: | https://doi.org/10.1073/pnas.1812963116 |
ISSN: | 1091-6490 |
Parent Title (English): | Proceedings of the National Academy of Sciences of the United States of America : PNAS |
Document Type: | Article (peer-reviewed) |
Language: | English |
Year of Completion: | 2019 |
Release Date: | 2021/05/05 |
Volume: | 116.2019 |
Issue: | 7 |
First Page: | 2551 |
Last Page: | 2560 |
Open-Access-Status: | Open Access |
Licence (German): | ![]() |